Code: 07310
5 x 2 ml
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INTENDED USE
Lupus Anticoagulants (LA) are antibodies of the IgG and IgM type which are directed against a variety of anionic phospholipids. The presence of LA in plasma is increasingly associated with a variety of haemostatic problems such as recurrent foetal loss, thrombocytopenia, unexplained thrombosis and neurological disorders. LA prolongs phospholipid dependant in vitro clotting assays such as the activated partial thromboplastin time (aPTT). The Diagon DRVVT Screen (Cat.No.:07310) kit is intended for the qualitative determination of LA in human plasma. Russell?s Viper venom directly activates Factor X to Factor Xa in the presence of phospholipid and calcium, leading to detectable clot formation in plasma. The Dia-DRVVT Screen kit is more sensitive for LA than the aPTT. The Dia-DRVVT Screen kit is intended to be used in conjunction with the Dia- DRVVT Confirm kit (Cat.No.:07405).